ML-7

Overview

ML-7 is a selective and highly specific myosin light chain kinase ( MLCK ) inhibitor that acts as a trabecular meshwork (TM) relaxant. ML-7 enhances Quinocetone ( HY-123581 )-induced phosphorylation of ERK , p38 MAPK and JNK , attenuates Akt activation, and promotes apoptosis of hepatocellular carcinoma cells. ML-7 reduces Th2 cytokine secretion by inhibiting MLCK, while alleviating smooth muscle hyperplasia and collagen deposition . As a non-antibiotic adjuvant , ML-7 restores the sensitivity of drug-resistant bacteria to Tigecycline ( HY-B0117 ) . ML-7 can be used in research related to glaucoma, hepatocellular carcinoma, asthma, and Klebsiella pneumoniae infection .

Application

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Product Information

• Catalog No.: HY-119038
• CAS No.: 109376-83-2
• Molecular Formula: C15H17IN2O2S
• Molecular Weight: 416.28
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source