AW-814141

Overview

AW-814141 is a selective and orally active p38 MAP kinase inhibitor. AW-814141 has an IC 50 values of 100 nM and 158 nM for p38-α and β isoforms, respectively. AW-814141 can inhibit the production of TNF-α induced by LPS ( HY-D1056 ). AW-814141 can inhibit paw edema in rats in a dose-dependent manner. AW-814141 exhibits anti-inflammatory activity and can be used in the research of inflammatory diseases such as rheumatoid arthritis.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > p38 MAPK

Product Information

• Catalog No.: HY-119298
• CAS No.: 905285-51-0
• Molecular Formula: C22H25N5O
• Molecular Weight: 375.47
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source