7-Azido-4-methylcoumarin

Overview

7-Azido-4-methylcoumarin is a selective coumarin-based fluorescent probe for hydrogen sulfide (H 2 S). In the presence of H 2 S, the aromatic azido group of 7-Azido-4-methylcoumarin is selectively reduced to produce the fluorescently active 7-amino-4-methylcoumarin (AMC). 7-Azido-4-methylcoumarin binds to the coumarin/phenol-binding site of BSA , the aglycone-binding site of UGT1A6 , and the substrate-binding site of SULT1A1 , respectively. 7-Azido-4-methylcoumarin retains its fluorescent properties after covalent binding, acts as a fluorescent H 2 S probe, and does not react with cysteine, homocysteine or glutathione (Ex/Em = 340/445 nm).

Application

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Product Information

• Catalog No.: HY-119323
• CAS No.: 95633-27-5
• Molecular Formula: C10H7N3O2
• Molecular Weight: 201.18
• Purity: 98.90%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source