Fonsartan free acid

Overview

Fonsartan (HOE-720) free acid is an orally active angiotensin II receptor ( AT1R ) antagonist with an IC 50 value of 0.48 nM, exhibiting potent antihypertensive activity. Fonsartan free acid dose-dependently inhibits angiotensin II-induced pressor response in rats ( ID 50 = 0.11 mg/kg) and shows significant long-lasting blood pressure-lowering effects in high-renin animal models. Fonsartan free acid is primarily used in research on hypertension and cardiovascular diseases.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Angiotensin Receptor

Product Information

• Catalog No.: HY-119379
• CAS No.: 144628-52-4
• Molecular Formula: C26H32N4O5S2
• Molecular Weight: 544.69
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source