JAK3 covalent inhibitor-1 is a potent and selective janus kinase 3 ( JAK3 ) covalent inhibitor with an IC 50 of 11 nM and shows 246-fold selectivity vs other JAKs.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > JAK/STAT Signaling | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > JAK
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