PF-06446846 hydrochloride

Overview

PF-06446846 hydrochloride is an orally active and highly selective inhibitor of translation of Proprotein convertase subtilisin/kexin type 9 ( PCSK9 ) . PF-06446846 hydrochloride inhibits PCSK9 by inducing the ribosome to stall around codon 34.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > PCSK9

Product Information

• Catalog No.: HY-120088A
• CAS No.: 1632250-50-0
• Molecular Formula: C22H21Cl2N7O
• Molecular Weight: 470.35
• Purity: 99.44%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 2 years; -20°C, 1 year (sealed storage, away from moisture)
• Solubility: ≥ 5 mg/mL (10.63 mM); Clear solution
• Availability: In-stock

Source

Original product source