TAS05567

Overview

TAS05567 is a potent, highly selective, ATP-competitive and orally active Syk inhibitor with an IC 50 of 0.37 nM. In a panel of 192 kinases, TAS05567 only shows >70% inhibition of Syk and 4 other kinases ( FLT3 , JAK2 , KDR and RET with IC 50 s of 10 nM, 4.8 nM, 600 nM and 29 nM, respectively). TAS05567 can be used for humoral immune-mediated inflammatory conditions such as autoimmune and allergic diseases.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Syk | Products > Signaling Pathways > RET

Product Information

• Catalog No.: HY-120214
• CAS No.: 1429038-15-2
• Molecular Formula: C21H29N9O2
• Molecular Weight: 439.51
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source