[2-(aminomethyl)phenyl]methanol

[2-(aminomethyl)phenyl]methanol
  • CAS No.:4152-92-5

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
[2-(aminomethyl)phenyl]methanol Basic information
Product Name:[2-(aminomethyl)phenyl]methanol
Synonyms:[2-(aminomethyl)phenyl]methanol;RARECHEM GT HW 0287;UKRORGSYN-BB BBV-182531;o-(Hydroxymethyl)benzylamine
CAS:4152-92-5
MF:C8H11NO
MW:137.18
EINECS:
Product Categories:
Mol File:4152-92-5.mol
[2-(aminomethyl)phenyl]methanol Chemical Properties
Boiling point 271℃
density 1.113
Fp 118℃
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka14.28±0.10(Predicted)
Safety Information
MSDS Information
[2-(aminomethyl)phenyl]methanol Usage And Synthesis
Uses[2-(aminomethyl)phenyl]methanol can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Uses(2-(Aminomethyl)phenyl)methanol is a useful research intermediate for the total synthesis of Adalinine.
Synthesis(4-Aminomethyl-phenyl)-methanol hydrochloride salt 4-Hydroxymethyl-benzonitrile (2.0 g, 15 mol) was reduced using Raney nickel (0. 5g) and hydrogen (50 psi) in MeOH: NH3 (100ml) for 20 hours. The reaction mixture was filtered through a pad of celite. The filtrate was concentrated under reduced pressure to afford (4-aminomethyl-phenyl)-methanol hydrochloride salt (2.01 g, 98percent) as a white solid of sufficient purity for use without further purification: MS (APCI+) : m/z 138.3 (M+H).
[2-(aminomethyl)phenyl]methanol Preparation Products And Raw materials

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