TH1338

Overview

TH1338 (compound 3b), an orally active camptothecin derivative and a potent chemotherapeutic agent for cancer , demonstrates excellent cytotoxic potency against human tumor cell lines in vitro. TH1338 (compound 3b) possesses significant brain penetration, favorable efflux pump properties, and hematological toxicity profile.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Lung Cancer | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > ADC Payloads | Products > Signaling Pathways > Topoisomerase

Product Information

• Catalog No.: HY-120574
• CAS No.: 1258494-60-8
• Molecular Formula: C22H21N3O4
• Molecular Weight: 391.42
• Purity: 98.77%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 1.82 mg/mL (4.65 mM); Clear solution
• Availability: In-stock

Source

Original product source