T-1840383 is a potent, ATP-competitive inhibitor of c-Met/VEGFR-2 , with the IC 50 s of 1.9 nM, 7.7 nM, 2.2 nM and 5.5 nM for c-Met , VEGFR1 , VEGFR2 and VEGFR3 , respectively.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > c-Met/HGFR | Products > Signaling Pathways > VEGFR
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