PF-06761281

Overview

PF-06761281 (Compound 4a) is a potent, orally active, partial selective sodium-coupled citrate transporter (NaCT or SLC13A5) inhibitor with IC 50 values of 0.51, 13.2 and 14.1 µM against HEK NaCT , HEK NaDC1 and HEK NaDC3 , respectively.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Sodium Channel

Product Information

• Catalog No.: HY-120669
• CAS No.: 1854061-19-0
• Molecular Formula: C13H17NO6
• Molecular Weight: 283.28
• Purity: 99.52%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: 2.5 mg/mL (8.83 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source