LDN193189

Overview

LDN193189 (DM-3189) is a potent selective BMP type I receptor (BMP I) inhibitor. LDN193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC 50 values of 5 nM and 30 nM, respectively. LDN193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva.

Application

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Product Information

• Catalog No.: HY-12071
• CAS No.: 1062368-24-4
• Molecular Formula: C25H22N6
• Molecular Weight: 406.49
• Purity: 99.72%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: 1 mg/mL (2.46 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source