PF-04822163 is an orally active, selective, and blood-brain barrier permeable PDE1 inhibitor with IC 50 values of 2 nM, 2.4 nM, and 7 nM for PDE1A , PDE1B , and PDE1C respectively. PF-04822163 can be used in the research of attention deficit hyperactivity disorder or Parkinson's disease.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Phosphodiesterase (PDE)
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