SR1555

Overview

SR1555 is a specific retinoic acid receptor-related orphan nuclear receptor γ ( RORγ ) inverse agonist with an IC 50 value of 1 μM. SR1555 not only inhibits TH17 cell development and function but also increases the frequency of T regulatory cells, as well as inhibits the expression of IL-17 . SR1555 can be used for researching autoimmune diseases.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > ROR

Product Information

• Catalog No.: HY-120785
• CAS No.: 1386439-51-5
• Molecular Formula: C22H22F6N2O2
• Molecular Weight: 460.41
• Purity: 99.69%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (5.43 mM); Clear solution
• Availability: In-stock

Source

Original product source