BI 186908

Overview

BI 186908 is a selective and orally active MCH receptor 1 antagonist with an IC 50 of 22 nM and a K i of 14 nM. BI 186908 binds with comparably high affinity to the recombinant human, cynomolgus monkey ( IC 50 of 18 nM), dog ( IC 50 of 23 nM) and rat ( IC 50 of 18 nM) MCH-R1. BI 186908 can significantly reduce the body weight of diet-induced obese rats. BI 186908 can be used for the study of obesity.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Obesity | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Metabolic Disease | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > MCHR1 (GPR24)

Product Information

• Catalog No.: HY-120847
• CAS No.: 1453500-36-1
• Molecular Formula: C23H26N4O4
• Molecular Weight: 422.48
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source