N-Arachidonoyl-L-serine

Overview

N-Arachidonoyl-L-serine (ARA-S) is an endocannabinoid. N-Arachidonoyl-L-serine induces phosphorylation of Akt and MAPK in endothelial cells. N-Arachidonoyl-L-serine also induces endothelium-dependent vasodilation in isolated rat mesenteric and abdominal aortas. N-Arachidonoyl-L-serine exhibits neuroprotective effects after traumatic brain injury by reducing apoptosis . N-Arachidonoyl-L-serine promotes the opening of KV7.1 /KCNE1 channels in mammalian cells and shortens the action potential duration in cardiomyocytes. N-Arachidonoyl-L-serine may be used in research on cardiovascular and cerebrovascular diseases and neurological disorders.

Application

Products | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Akt | Products > Signaling Pathways > p38 MAPK | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Potassium Channel

Product Information

• Catalog No.: HY-120960
• CAS No.: 187224-29-9
• Molecular Formula: C23H37NO4
• Molecular Weight: 391.54
• Purity: 98%
• Storage: Solution, -20°C, 2 years
• Availability: In-stock

Source

Original product source