Anagyrine ((-)-Anagyrine) is a quinolizidine alkaloid that has been found in Lupinus albus . Anagyrine binds to muscarinic and nicotinic acetylcholine receptors with IC 50 values of 132 and 2096 µM respectively. Anagyrine is a potent and effective desensitizer of nAChR , and Anagyrine can directly, without metabolism, desensitize nAChR .
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