Eggmanone

Overview

Eggmanone (EGM1) is a potent and selective phosphodiesterase 4 ( PDE4 ) antagonist with an IC 50 of 72 nM for PDE4D3. Eggmanone shows approximately 40- to 50-fold selective for PDE4D3 over other PDEs. Eggmanone exerts its Hh-inhibitory effects through selective antagonism of PDE4 , leading to protein kinase A activation and subsequent Hh blockade.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Phosphodiesterase (PDE)

Product Information

• Catalog No.: HY-121037
• CAS No.: 505068-32-6
• Molecular Formula: C20H20N2O2S3
• Molecular Weight: 416.58
• Purity: 95.31%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source