Mesembrine ((+)-Mesembrine) a main alkaloid that features an aryloctahydroindole skeleton. Mesembrine is a 5-HT transporter inhibitor with a K i of 1.4 nM. Mesembrine also inhibits phosphodiesterase 4B (PDE4B) with an IC 50 of 7.8 μM.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > 5-HT Receptor | Products > Signaling Pathways > Phosphodiesterase (PDE)
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