1,4-DPCA

Overview

1,4-DPCA, a potent prolyl-4-hydroxylase inhibitor, is a collagen hydroxylation inhibitor in human foreskin fibroblasts with an IC 50 of 2.4 µM. 1,4-DPCA inhibits prolyl-4-hydroxylases α isoforms stabilizes HIF-1α protein. 1,4-DPCA also inhibits factor inhibiting HIF (FIH) with an IC 50 of 60 μM.

Application

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Product Information

• Catalog No.: HY-121172
• CAS No.: 331830-20-7
• Molecular Formula: C13H8N2O3
• Molecular Weight: 240.21
• Purity: 99.78%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 0.92 mg/mL (3.83 mM); Clear solution
• Availability: In-stock

Source

Original product source