CP 154526 is a potent, brain-penetrant and selective corticotropin-releasing factor receptor 1 (CRF1) antagonist with a K i of 2.7 nM. CP 154526 shows selective for CRF1 over CRF2 (K i = >10 μM). CP 154526 has anxiolytic activities.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > CRFR
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