K-8012

Overview

K-8012 is a Sulindac ( HY-B0008 ) analog and RXRα antagonist with an IC 50 of 9.2 µM. K-8012 inhibits the activation of AKT . K-8012 induces Apoptosis , redirecting the TNFα signaling pathway from survival to death. K-8012 exerts anticancer activity against lung cancer , prostate cancer , and breast cancer . K-8012 can be used in research related to lung cancer , prostate cancer , breast cancer , and hepatocellular carcinoma.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Lung Cancer | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Prostate Cancer | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Liver Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Others | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Drug Derivative | Products > Signaling Pathways > TNF Receptor | Products > Signaling Pathways > RAR/RXR | Products > Signaling Pathways > Akt | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-121435
• CAS No.: 1346513-17-4
• Molecular Formula: C23H23FN4
• Molecular Weight: 374.45
• Purity: 99.51%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source