CCMI

Overview

CCMI (AVL-3288) is a potent and selective α7 nAChR -positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs. CCMI has potential in CNS diseases with cognitive dysfunction.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Alzheimer's Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > nAChR

Product Information

• Catalog No.: HY-12150
• CAS No.: 917837-54-8
• Molecular Formula: C19H15Cl2N3O2
• Molecular Weight: 388.25
• Purity: 99.97%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.08 mg/mL (5.36 mM); Clear solution
• Availability: In-stock

Source

Original product source