GSK2332255B is a potent, selective TRPC3 and TRPC6 antagonist with IC 50 s of 5 nM and 4 nM for rat TRPC3 and rat TRPC6 . GSK2332255B shows ≥100-fold selectivity for TRPC3/6 over other calcium-permeable channels.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > TRP Channel
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