(5Z,2E)-CU-3

Overview

(5Z,2E)-CU-3 is an isomer of CU-3 ( HY-121638 ). CU-3 is a DGKα inhibitor with an IC 50 of 0.6 μM. CU-3 competitively reduces DGKα’s affinity for ATP via binding to the enzyme’s catalytic region. CU-3 induces apoptosis in cancer cells. CU-3 promotes T-cell activation and enhances IL-2 production. CU-3 can be used for the research of hepatocellular carcinoma and cervical cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > DGK | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > Caspase

Product Information

• Catalog No.: HY-121638A
• CAS No.: 1815598-71-0
• Molecular Formula: C16H12N2O4S3
• Molecular Weight: 392.47
• Purity: 95.03%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: 2 mg/mL (5.10 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source