(Z)-KC02

Overview

(Z)-KC02 is an inhibitor of ABHD16A, the phosphatidylserine (PS) lipase that produces lyso-PS. Lysophosphatidylserine (lyso-PS) is a signaling lipid that regulates immune and neurological processes. It is associated with several neurological disorders such as retinitis pigmentosa and cataracts (PHARC). (Z)-KC02 depletes lyso-PS in lymphoblasts from PHARC subjects. (Z)-KC02 also reduces lyso-PS and lipopolysaccharide-induced cytokine production in macrophages and modulates lyso-PS metabolism in vivo.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > TNF Receptor

Product Information

• Catalog No.: HY-121892
• CAS No.: 1646795-60-9
• Molecular Formula: C17H21NO3
• Molecular Weight: 287.35
• Purity: 99.98%
• Storage: Solution, -20°C, 2 years
• Availability: In-stock

Source

Original product source