Combretastatin A-1

Overview

Combretastatin A-1 is a microtubule polymerization inhibitor that binds to the colchicine-binding site of tubulin. Combretastatin A-1 inhibits the Wnt/β-catenin pathway through tubulin depolymerization mediated AKT deactivation. Combretastatin A-1 exhibits anti-tumor and anti-vascular effects.

Application

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Product Information

• Catalog No.: HY-121993
• CAS No.: 109971-63-3
• Molecular Formula: C18H20O6
• Molecular Weight: 332.35
• Purity: 97.03%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (6.26 mM); Clear solution
• Availability: In-stock

Source

Original product source