PF-05186462

Overview

PF-05186462 is a potent and selective inhibitor of human Nav1.7 voltage-dependent sodium channel , with an IC 50 of 21 nM. PF-05186462 shows significant selectivity for Nav1.7 versus other sodium channels (Nav 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, and 1.8). PF-05186462 can be used for the research of acute or chronic pain.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Sodium Channel

Product Information

• Catalog No.: HY-122001
• CAS No.: 1235406-03-7
• Molecular Formula: C19H10ClF4N5O3S2
• Molecular Weight: 531.89
• Purity: 99.69%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (4.70 mM); Clear solution
• Availability: In-stock

Source

Original product source