MK181 is an aldose reductase (AR) inhibitor with IC 50 s of 0.71 μM and 4.5 μM for aldose reductase and AKR1B10 , respectively. MK181 can bind into the external loop A subpocket of AKR1B10.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Aldose Reductase
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