AC-73

Overview

AC-73 is a first specific, orally active inhibitor of cluster of differentiation 147 ( CD147 ) , which specifically disrupts CD147 dimerization, thereby mainly suppressing the CD147 /ERK1/2/STAT3/MMP-2 pathways. AC-73 inhibits the motility and invasion of hepatocellular carcinoma cells. AC-73 is also an anti-proliferative agent and an inducer of autophagy in leukemic cells.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Liver Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > Autophagy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Autophagy

Product Information

• Catalog No.: HY-122214
• CAS No.: 775294-71-8
• Molecular Formula: C21H21NO2
• Molecular Weight: 319.40
• Purity: 99.91%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.08 mg/mL (6.51 mM); Clear solution
• Availability: In-stock

Source

Original product source