GBR 12935

Overview

GBR 12935 is a potent, and selective dopamine reuptake inhibitor, with the binding constant (K d ) of 1.08 nM in COS-7 cells. GBR 12935 stimulates the locomotion activity in different mice strains but fails to induce stereotypy. Thus, GBR 12935 also prevents the d-Fenfluramine-induced head-twitch response in mice.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Dopamine Transporter

Product Information

• Catalog No.: HY-12242A
• CAS No.: 76778-22-8
• Molecular Formula: C28H34N2O
• Molecular Weight: 414.58
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source