BRD6989

Overview

BRD6989, an analog of the natural product cortistatin A (dCA), inhibits CDK8 and upregulates IL-10 . BRD6989 selectively binds a complex of CDK8 with an IC 50 of ~200 nM. BRD6989 inhibits the kinase activity of recombinant CDK8 or CDK19 complexes.

Application

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Product Information

• Catalog No.: HY-122586
• CAS No.: 642008-81-9
• Molecular Formula: C16H16N4
• Molecular Weight: 264.33
• Purity: 99.54%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (7.87 mM); Clear solution
• Availability: In-stock

Source

Original product source