MALT1 inhibitor MI-2

Overview

MALT1 inhibitor MI-2 is a MALT1 inhibitor ( IC 50 =5.84 μM). MALT1 inhibitor MI-2 binds directly to MALT1 , irreversibly suppresses protease function and is accompanied by NF-κB reporter activity suppression, c-REL nuclear localization inhibition, and NF-κB target gene downregulation. MALT1 inhibitor MI-2 shows nontoxic to animals .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > NF-κB | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > MALT1

Product Information

• Catalog No.: HY-12276
• CAS No.: 1047953-91-2
• Molecular Formula: C19H17Cl3N4O3
• Molecular Weight: 455.72
• Purity: 99.73%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (5.49 mM); Clear solution
• Availability: In-stock

Source

Original product source