K02288 is a potent bone morphogenetic protein (BMP) type I receptor inhibitor with IC 50 s of 1.8, 1.1, 6.4 nM for ALK1 , ALK2 and ALK6 , respectively. K02288 shows slightly weaker inhibition against ALK3 and ALK6 with IC 50 s of of 5-34 nM.
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