Ifebemtinib (BI 853520) is an orally active and potent focal adhesion kinase ( FAK ) inhibitor (recombinant FAK IC 50 =1 nM). Ifebemtinib shows anti-proliferative activity against cancer cells. Ifebemtinib inhibits FER Kinase and FES Kinase with IC 50 s of 900 nM and 1040 nM, respectively.
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