RAS inhibitor Abd-7

Overview

RAS inhibitor Abd-7, a potent RAS-binding compound ( K d =51 nM), is a RAS-effector protein-protein interaction (PPI) inhibitor. RAS inhibitor Abd-7 interacts with RAS inside the cells, prevents RAS-effector interactions and inhibits endogenous RAS-dependent signaling. RAS inhibitor Abd-7 impairs the PPI of various mutant KRAS proteins with PI3K , CRAF and RALGDS as well as NRAS Q61H and HRAS G12V.

Application

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Product Information

• Catalog No.: HY-122862
• CAS No.: 2351843-48-4
• Molecular Formula: C23H25N3O3
• Molecular Weight: 391.46
• Purity: 99.57%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.08 mg/mL (5.31 mM); Clear solution
• Availability: In-stock

Source

Original product source