PEAQX (NVP-AAM077) is an orally active and selective NMDA antagonist, with IC 50 values of 270 nM and 29.6 μM for hNMDAR 1A/2A and hNMDAR 1A/2B , respectively. PEAQX can promote the activation of caspase-3 and induce cell apoptosis in cortical striatal slice cultures.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > iGluR
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