Moracin M is a phenolic component that can be isolated from Mori Cortex , is a potent phosphodiesterase-4 ( PDE4 ) inhibitor with IC 50 values of 2.9, 4.5, >40, and >100 μM for PDE4D2, PDE4B2, PDE5A1, and PDE9A2, respectively. Moracin M has anti-inflammatory activity.
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