Navtemadlin

Overview

Navtemadlin (AMG 232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction, with an IC 50 of 0.6 nM. Navtemadlin binds to MDM2 with a K d of 0.045 nM.

Application

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Product Information

• Catalog No.: HY-12296
• CAS No.: 1352066-68-2
• Molecular Formula: C28H35Cl2NO5S
• Molecular Weight: 568.55
• Purity: 99.17%
• Storage: Powder -20°C, 3 years , 4°C, 2 years * The compound is unstable in solutions, freshly prepared is recommended.
• Solubility: ≥ 2.5 mg/mL (4.40 mM); Clear solution
• Availability: In-stock

Source

Original product source