(-)-Indolactam V

Overview

(-)-Indolactam V is a PKC activator, with K i s of 3.36 nM, 1.03 μM for η-CRD2 ( PKCη surrogate peptide), γ-CRD2 ( PKCγ surrogate peptide), and K d s of 5.5 nM (η-C1B), 7.7 nM (ε-C1B), 8.3 nM (δ-C1B), 18.9 nM (β-C1A-long), 20.8 nM (α-C1A-long), 137 nM (β-C1B), 138 nM (γ-C1A), 213 nM (γ-C1B), and has antitumor activity.

Application

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Product Information

• Catalog No.: HY-12307
• CAS No.: 90365-57-4
• Molecular Formula: C17H23N3O2
• Molecular Weight: 301.38
• Purity: 98.42%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (8.30 mM); Clear solution
• Availability: In-stock

Source

Original product source