Pifithrin-α, p-Nitro, Cyclic

Overview

Pifithrin-α, p-Nitro, Cyclic (PFN-α) is cell-permeable and active-form p53 inhibitor. Pifithrin-α, p-Nitro, Cyclic is one order magnitude more active than Pifithrin-α in protecting cortical neurons exposed to Etoposide (ED 50 =30 nM). Pifithrin-α, p-Nitro, Cyclic behaves as a p53 posttranscriptional activity inhibitor. Pifithrin-α, p-Nitro, Cyclic do not prevent p53 phosphorylation on the S15 residue.

Application

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Product Information

• Catalog No.: HY-123076
• CAS No.: 60477-38-5
• Molecular Formula: C15H13N3O2S
• Molecular Weight: 299.35
• Purity: 99.37%
• Storage: -20°C, stored under nitrogen * In solvent : -80°C, 2 years; -20°C, 1 year (stored under nitrogen)
• Availability: In-stock

Source

Original product source