FTI-2153

Overview

FTI-2153 is a potent and highly selective inhibitor of farnesyltransferase (FTase) , with an IC 50 of 1.4 nM. FTI-2153 is >3000-fold more potent at blocking H-Ras ( IC 50 , 10 nM) than Rap1A processing. Anti-cancer activity.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Lung Cancer | Products > Disease Areas > Pancreatic Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Farnesyl Transferase

Product Information

• Catalog No.: HY-123242
• CAS No.: 344900-92-1
• Molecular Formula: C25H30N4O3S
• Molecular Weight: 466.60
• Purity: 99.77%
• Storage: -20°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (5.36 mM); Clear solution
• Availability: In-stock

Source

Original product source