UNC0379 TFA is a selective, substrate-competitive inhibitor of lysine methyltransferase SETD8 ( KMT5A ) with an IC 50 of 7.3 μM, K D value of 18.3 μM. UNC0379 TFA can be used in the research of inflammation and cancers, such as pulmonary fibrosis, ovarian cancer , neuroblastoma.
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