Ubrogepant

Overview

Ubrogepant (MK-1602) is an orally active and selective antagonist of calcitonin gene-related peptide receptor ( CGRP ). Ubrogepant has high affinity for CGRP receptors in human and rhesus monkeys, and can effectively block the cAMP response stimulated by α-CGRP . Ubrogepant can be used in the study of acute migraine.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > CGRP Receptor

Product Information

• Catalog No.: HY-12366
• CAS No.: 1374248-77-7
• Molecular Formula: C29H26F3N5O3
• Molecular Weight: 549.54
• Purity: 99.90%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 6.25 mg/mL (11.37 mM); Clear solution
• Availability: In-stock

Source

Original product source