VK4-116

Overview

VK4-116 (Compound 19) is a selective Dopamine D3 receptor (D3R) antagonist with a K i of 6.84 nM.VK4-116 significantly inhibits Oxycodone-induced hyperlocomotion and locomotor sensitization in mouse models. VK4-116 with pretreatment also inhibits the acquisition of Oxycodone-induced conditioned place preference (CPP) in rat models.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Behavioral Addiction | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Dopamine Receptor

Product Information

• Catalog No.: HY-123889
• CAS No.: 1982347-43-2
• Molecular Formula: C26H33ClN4O3
• Molecular Weight: 485.02
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source