HS56

HS56
  • CAS No.:922050-57-5
  • Grade:99.6%
  • Formula:C13H8ClN5OS
  • M.W.:317.75

Overview

HS56 is an ATP-competitive dual Pim/DAPK3 inhibitor with K i values of 0.26, 0.208, 2.94, and >100 μM for DAPK3, Pim-3, Pim-1, and Pim-2, respectively. HS56 inhibits LC20 phosphorylation and smooth muscle contraction. HS56 decreases blood pressure in spontaneously hypertensive mice. HS56 can be used in research of hypertension.

Application

Products | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Pancreatic Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Obesity | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Digestive System Disease | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Pim | Products > Signaling Pathways > DAPK

Product Information

  • Catalog No.: HY-123983
  • CAS No.: 922050-57-5
  • Molecular Formula: C13H8ClN5OS
  • Molecular Weight: 317.75
  • Purity: 99.6%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Availability: In-stock

Source

Original product source


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