ADM 12

Overview

ADM 12 is a highly selective transient receptor potential ankyrin 1 ( TRPA1 ) channel antagonist. ADM 12 blocks nitroglycerin (NTG)-induced trigeminal hyperalgesia in animal models, reducing expression of pain-related genes ( c-Fos , TRPA1) and neuropeptides (CGRP, SP). ADM_12 is promising for research of migraine and neuropathic pain.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > TRP Channel

Product Information

• Catalog No.: HY-124277
• CAS No.: 1644134-60-0
• Molecular Formula: C11H21NO4S3
• Molecular Weight: 327.48
• Purity: 98.86%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (7.63 mM); Clear solution
• Availability: In-stock

Source

Original product source