JNJ525

Overview

JNJ525 is a TNFα inhibitor with IC 50 values of 1.2 μM and 1.1 μM against TNFR1 and TNFR2 , respectively. JNJ525 forms ordered aggregates and induces quaternary structural transition of TNFα , thereby blocking the protein-protein interaction between TNFα and its receptors. The inhibitory activity of JNJ525 is completely lost in the presence of 0.1% Triton X-100.

Application

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Product Information

• Catalog No.: HY-124339
• CAS No.: 2092913-64-7
• Molecular Formula: C31H30N8
• Molecular Weight: 514.62
• Purity: 99.93%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source