UNC4203

CAS No.：1818234-19-3
Grade：99.80%
Formula：C30H44N6O
M.W.：504.71
Solvent：≥ 2.5 mg/mL (4.95 mM); Clear solution

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Overview

UNC4203 is a potent, orally available and highly selective MERTK inhibitor, with IC 50 s of 1.2 nM, 140 nM, 42 nM and 90 nM for MERTK, AXL , TYRO3 and FLT3 , respectively.

Application

Products | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Prostate Cancer | Products > Disease Areas > Urogenital Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > TAM Receptor | Products > Signaling Pathways > FLT3

Product Information

Catalog No.: HY-124502
CAS No.: 1818234-19-3
Molecular Formula: C30H44N6O
Molecular Weight: 504.71
Purity: 99.80%
Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solubility: ≥ 2.5 mg/mL (4.95 mM); Clear solution
Availability: In-stock

Source

Original product source

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