Burimamide is a blocker of histamine H2-receptor . Burimamide inhibits gastric acid secretion evoked by Pentagastrin ( HY-A0261 ) or Gastrin . Burimamide also has alpha-adrenoceptor blocking activity. Burimamide in combination with the H1-receptor antagonist Mepyramine ( HY-B1281 ) shows anti-inflammatory activity in a rat paw edema model induced by Compound 48/80 ( HY-115768 ).
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